Identifying and validating alternative splicing events in miami
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Different splicing is a imperative process for regulating rna expression and promoting proteomic diversity.
It plays a key role in tissue-specific expressed genes. This specificity is mainly regulated by way of splicing factors that jam to specific sequences cryed splicing regulatory elements SREs. Here, we report a genome-wide analysis to office alternative splicing on numerous tissues, including brain, callousness, liver, and muscle.
We propose a pipeline in the direction of identify differential exons crosswise tissues and hence tissue-specific SREs. Rencontre coquine par region.
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Identifying and validating alternative splicing events feature in miami Alternative splicing AS is a major source of variability in the transcriptome of eukaryotes. There is an increasing interest in its role in different pathologies. Before sequencing technology appeared, AS was measured with specific arrays. However, these arrays did not perform well in the detection of AS events and provided very large false discovery rates FDR. Recently the Human Transcriptome Array 2.
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